- SID is common in patients with haematological malignancies such as chronic lymphocytic leukaemia or multiple myeloma.1
- Novel oncological therapies and resulting increased long-term survival of patients make SID more prevalent than ever.1
- For example, multiple myeloma patients have a 7-fold higher risk of developing bacterial infections and even a 10-fold increased risk for viral infections. Furthermore, up to 22% of deaths in these patients could be due to infections.2
Infections are a major cause of morbidity and mortality in haematological malignancies.2,3
References
- Sánchez-Ramón S, et al. Primary and Secondary Immunodeficiency Diseases in Oncohaematology: Warning Signs, Diagnosis, and Management. Front Immunol. 2019; 10: 586.
- Blimark C, et al. Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patients. Haematologica. 2015; 100:107-13.
- Nosari A. Infectious complications in chronic lymphocytic leukemia. Mediterr J Hematol Infect Dis. 2012;4(1):e2012070.